Dec 25 2009

Sleep Patterns Influence Of Genes

Scientists say they have found evidence that the habit of waking and sleeping late can be caused by a single gene.
Researchers say these findings have helped to better understand how the human body and its influence on sleep disorders.

As they say, to bed early, waking up too early. However, researchers in the world of sleep problems, an increase could be called a disease, the symptoms of people who have trouble sleeping at night.

With the human body works 24-hour cycle. This natural mechanism is known as the circadian rhythm, which determines the time to sleep and when.

Researchers, including a neurologist. Louis Ptacek Howard Hughes Medical Institute, has found a defect in a gene known as Per2 circadian rhythms that govern it.

In the journal Nature, Dr. Ptacek and his colleagues at the Howard Hughes Institute, University of San Francisco Califirnia reported the discovery of another gene mutation in another gene called CK1 delta.

“If you imagine that the rotation of gears in a matter of hours, if the movement is too fast, perhaps there is a problem in one wheel, or in the Per2 gene, mutations can also occur during a different conference in this case CK1 Delta, “said Dr. Ptacek who discovered the existence of a defective gene in a family of people who get up early.

When the gene was inserted into the body of rats, the animals showed similar behavior. When injections of the same gene in Drosophila that alter their circadian rhythm.

Mr. Ptacek stated that the use of a single gene to study the behavior of different species can be medorong discovery of molecular mechanisms involved in sleep disorders. About three in 10 people has some type of sleep disorders. The search for genes that regulate the biological clock may lead to the discovery of drugs for sleep disorders in people.

“As we get older, we all have a tendency to sleep early and rise early. In some cases, has become a problem for seniors who woke up cold, it was a dark and lonely. Thus, the discovery of what we call normal with age is increasing in drugs is another example that helps us to adjust your clock will likely improve the quality of life, “said Ptacek.

Investigators said that six members of family who attended rising early is also suffering from asthma, depression and headaches. Scientists believe there may be a link between these diseases and sleep disorders.

Tom reflexology Feroah Medical College of Wisconsin in Milwaukee studied rats that were almost identical to each other and celebrate a variety of different genes with different characteristics of sleep.

Professor Feroah say no wonder that people who suffer from sleep disorders suffered from various diseases. He said that circadian clocks regulate small circuits in each cell that ultimately regulate the immune system, temperature regulation, hormones and brain function of the brain.

“There is a combination of all bodily functions, what we are trying to sleep habit, because they use the television because there are lights that seemed to disrupt our lives features the entire organization. It makes us feel more stress and also to relieve stress, not sleeping well, has not recovered to normal when they are sick and tend to suffer from the disease, “said Feroah.

People whose sleep is not good and could not sleep properly, suffer more heart disease, hypertension and stroke, which caused disruption in the immune system,

The researchers hope to find genes sleep more. Laboratory studies to date show little change in the activities CK1 delta gene seems to disturb the peaceful slumber of the protein. This is probably good news for people who can not sleep good night.

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